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2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05)
Registering Drosophila Embryos at Cellular Resolution to Build a Quantitative 3D Atlas of Gene Expression Patterns and Morphology
Stanford, California
August 08-August 11
ISBN: 0-7695-2442-7
ASCII Text
x 
 
Charless C. Fowlkes, Jitendra Malik, Cris L. Luengo Hendriks, Soile V. E. Keranen, Mark D. Biggin, David W. Knowles, Damir Sudar, "Registering Drosophila Embryos at Cellular Resolution to Build a Quantitative 3D Atlas of Gene Expression Patterns and Morphology," 2005 IEEE Computational Systems Bioinformatics Conference - Workshops, pp. 354-357, 2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05), 2005.
 
 
BibTex
x
 
@article{ 10.1109/CSBW.2005.118,
author = {Charless C. Fowlkes and Jitendra Malik and Cris L. Luengo Hendriks and Soile V. E. Keranen and Mark D. Biggin and David W. Knowles and Damir Sudar},
title = {Registering Drosophila Embryos at Cellular Resolution to Build a Quantitative 3D Atlas of Gene Expression Patterns and Morphology},
journal ={2005 IEEE Computational Systems Bioinformatics Conference - Workshops},
volume = {0},
year = {2005},
isbn = {0-7695-2442-7},
pages = {354-357},
doi = {http://doi.ieeecomputersociety.org/10.1109/CSBW.2005.118},
publisher = {IEEE Computer Society},
address = {Los Alamitos, CA, USA},
}
 
 
RefWorks Procite/RefMan/Endnote
x 
 
TY - CONF
JO - 2005 IEEE Computational Systems Bioinformatics Conference - Workshops
TI - Registering Drosophila Embryos at Cellular Resolution to Build a Quantitative 3D Atlas of Gene Expression Patterns and Morphology
SN - 0-7695-2442-7
SP354
EP357
A1 - Charless C. Fowlkes,
A1 - Jitendra Malik,
A1 - Cris L. Luengo Hendriks,
A1 - Soile V. E. Keranen,
A1 - Mark D. Biggin,
A1 - David W. Knowles,
A1 - Damir Sudar,
PY - 2005
KW - null
VL - 0
JA - 2005 IEEE Computational Systems Bioinformatics Conference - Workshops
ER -
 
Charless C. Fowlkes, University of California, Berkeley
Jitendra Malik, University of California, Berkeley
Cris L. Luengo Hendriks, Lawrence Berkeley National Laboratory
Soile V. E. Keranen, Lawrence Berkeley National Laboratory
Mark D. Biggin, Lawrence Berkeley National Laboratory
David W. Knowles, Lawrence Berkeley National Laboratory
Damir Sudar, Lawrence Berkeley National Laboratory

The Berkeley Drosophila Transcription Network Project is developing a suite of methods to convert volumetric data generated by confocal fluorescence microscopy into numerical, three dimensional representations of gene expression at cellular resolution. One key difficulty is that fluorescence microscopy can only capture expression levels for a few gene products in a given animal. We report on a method for registering 3D expression data from different Drosophila embryos stained for overlapping subsets of gene products in order to build a composite atlas, ultimately containing coexpression information for thousands of genes. Our techniques have also allowed the discovery of a complex pattern of cell density across the blastula that changes over time and may play a role in gastrulation.

Citation:
Charless C. Fowlkes, Jitendra Malik, Cris L. Luengo Hendriks, Soile V. E. Keranen, Mark D. Biggin, David W. Knowles, Damir Sudar, "Registering Drosophila Embryos at Cellular Resolution to Build a Quantitative 3D Atlas of Gene Expression Patterns and Morphology," csbw, pp.354-357, 2005 IEEE Computational Systems Bioinformatics Conference - Workshops (CSBW'05), 2005
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