A Pivoting Algorithm for Metabolic Networks in the Presence of Thermodynamic Constraints

CC
CSB
2005
2005 IEEE Computational Systems Bioinformatics Conference (CSB'05)
Abstract - A Pivoting Algorithm for Metabolic Networks in the Presence of Thermodynamic Constraints

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	Similar Articles Articles by R. Nigam Articles by S. Liang

2005 IEEE Computational Systems Bioinformatics Conference (CSB'05)

Stanford, California

August 08-August 11

ISBN: 0-7695-2344-7

	ASCII Text	x
	R. Nigam, S. Liang, "A Pivoting Algorithm for Metabolic Networks in the Presence of Thermodynamic Constraints," Computational Systems Bioinformatics Conference, International IEEE Computer Society, pp. 259-267, 2005 IEEE Computational Systems Bioinformatics Conference (CSB'05), 2005.

	BibTex	x
	@article{ 10.1109/CSB.2005.6, author = {R. Nigam and S. Liang}, title = {A Pivoting Algorithm for Metabolic Networks in the Presence of Thermodynamic Constraints}, journal ={Computational Systems Bioinformatics Conference, International IEEE Computer Society}, volume = {0}, year = {2005}, isbn = {0-7695-2344-7}, pages = {259-267}, doi = {http://doi.ieeecomputersociety.org/10.1109/CSB.2005.6}, publisher = {IEEE Computer Society}, address = {Los Alamitos, CA, USA}, }

	RefWorks Procite/RefMan/Endnote	x
	TY - CONF JO - Computational Systems Bioinformatics Conference, International IEEE Computer Society TI - A Pivoting Algorithm for Metabolic Networks in the Presence of Thermodynamic Constraints SN - 0-7695-2344-7 SP259 EP267 A1 - R. Nigam, A1 - S. Liang, PY - 2005 KW - null VL - 0 JA - Computational Systems Bioinformatics Conference, International IEEE Computer Society ER -

R. Nigam, Stanford University

S. Liang, University of Texas

DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/CSB.2005.6

A linear programming algorithm is presented to constructively compute thermodynamically feasible fluxes and change in chemical potentials of reactions for a metabolic network. It is based on physical laws of mass conservation and the second law of thermodynamics that all chemical reactions should satisfy. As a demonstration, the algorithm has been applied to the core metabolic pathway of E. coli.

Citation:

R. Nigam, S. Liang, "A Pivoting Algorithm for Metabolic Networks in the Presence of Thermodynamic Constraints," csb, pp.259-267, 2005 IEEE Computational Systems Bioinformatics Conference (CSB'05), 2005

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