This paper presents a new approach to generating configuration-oriented executable symbolic test sequences from Extended Finite State Machine (EFSM) models. The information about the values of the context variables and the domain intervals of the input parameters are exploited to guide the derivation of the test sequences. Meanwhile, the transition guards along the test sequences are continually used to reduce the domain intervals of the input parameters. Experiments indicate that this method significantly reduces the EFSM state space to be explored and the number of non-executable symbolic test sequences to be generated. Since parameterized input events are allowed to occur in EFSM cycles, this method is suitable for testing the open reactive systems that interact with the environments via parameterized input events.