In this paper we present the main concepts behind the Galaxy cluster management framework. Galaxy is focused on servicing large-scale enterprise clusters through the use of novel, highly scalable communication and management techniques. Galaxy is a flexible framework built upon the notion of low-level management of cluster farms, where within these farms islands of specific cluster management types can be created. A number of cluster profiles, which describe the components used in the different cluster types, are presented, as well as the components used in the management of these clusters.