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Twentieth IEEE International Symposium on Computer-Based Medical Systems (CBMS'07)
Statistical Comparison of Machine Learning Techniques for Treatment Optimisation of Drug-Resistant HIV-1
Maribor, Slovenia
June 20-June 22
ISBN: 0-7695-2905-4
Mattia CF Prosperi, University of Roma TRE, Italy
Giovanni Ulivi, University of Roma TRE, Italy
Maurizio Zazzi, University of Siena, Italy
Predicting the in-vivo effect of genotypic drug resistance of Human Immunodeficiency Virus type-1 (HIV-1) on response to antiretroviral therapies represents a major clinical issue. Different machine learning and feature selection methods are applied for the classification of treatment success, based on viral genotype, therapy and derived input features. The robustness of results is assessed through statistical validation. The procedures described are intended to be a general methodology in the challenging context of biology and medical science data mining.
Citation:
Mattia CF Prosperi, Giovanni Ulivi, Maurizio Zazzi, "Statistical Comparison of Machine Learning Techniques for Treatment Optimisation of Drug-Resistant HIV-1," cbms, pp.427-432, Twentieth IEEE International Symposium on Computer-Based Medical Systems (CBMS'07), 2007
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