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19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)
Analysis and Visualization of Proteomic Data by Fuzzy Labeled Self-Organizing Maps
Salt Lake City, Utah
June 22-June 23
ISBN: 0-7695-2517-1
Frank-Michael Schleif, Bruker Daltonik GmbH, Germany
Thomas Elssner, Bruker Daltonik GmbH, Germany
Markus Kostrzewa, Bruker Daltonik GmbH, Germany
Thomas Villmann, University Leipzig, Germany
Barbara Hammer, Clausthal University of Technology, Germany
We extend the self-organizing map in the variant as proposed by Heskes to a supervised fuzzy classification method. This leads to a robust classifier where efficient learning with fuzzy labeled or partially contradictory data is possible. Further, the integration of labeling into the location of prototypes in a self-organizing map leads to a visualization of those parts of the data relevant for the classification. The method is incorporated in a clinical proteomics toolkit dedicated for biomarker search which allows the necessary preprocessing and further data analysis with additional visualizations.
Index Terms:
fuzzy visualization, clinical proteomics, biomarker
Citation:
Frank-Michael Schleif, Thomas Elssner, Markus Kostrzewa, Thomas Villmann, Barbara Hammer, "Analysis and Visualization of Proteomic Data by Fuzzy Labeled Self-Organizing Maps," cbms, pp.919-924, 19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06), 2006
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