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19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)
JSSPrediction: a Framework to Predict Protein Secondary Structures Using Integration
Salt Lake City, Utah
June 22-June 23
ISBN: 0-7695-2517-1
L. Palopoli, Universita della Calabria, Italy
S. E. Rombo, Universita "Mediterranea" di Reggio Calabria, Italy
G. Terracina, Universita della Calabria, Italy
G. Tradigo, ICAR-CNR, Italy
P. Veltri, Universita "Magna Gr?cia" di Catanzaro, Italy
Identifying protein secondary structures is a difficult task. Recently, a lot of software tools for protein secondary structure prediction have been produced and made available on-line, mostly with good performances. However, prediction tools work correctly for families of proteins, such that users have to know which predictor to use for a given unknown protein. We propose a framework to improve secondary structure prediction by integrating results obtained from a set of available predictors. Our contribution consists in the definition of a two phase approach: (i) select a set of predictors which have good performances with the unknown protein family, and (ii) integrate the prediction results of the selected prediction tools. Experimental results are also reported.
Citation:
L. Palopoli, S. E. Rombo, G. Terracina, G. Tradigo, P. Veltri, "JSSPrediction: a Framework to Predict Protein Secondary Structures Using Integration," cbms, pp.931-935, 19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06), 2006
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