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14th IEEE Symposium on Computer-Based Medical Systems (CMBS'01)
Validation of a Na + - Ca ++ Regulation Model for High Variations of the Inner Cell Conditions
Bethesda, Maryland
March 26-March 27
ISBN: 0-7695-1004-3
ASCII Text
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V. González-Vélez, J. Aguilar-Pliego, J.D. Morales-Guzmán, J.R. Gonínez-Fernández, "Validation of a Na + - Ca ++ Regulation Model for High Variations of the Inner Cell Conditions," Computer-Based Medical Systems, IEEE Symposium on, pp. 0413, 14th IEEE Symposium on Computer-Based Medical Systems (CMBS'01), 2001.
 
 
BibTex
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@article{ 10.1109/CBMS.2001.941755,
author = {V. González-Vélez and J. Aguilar-Pliego and J.D. Morales-Guzmán and J.R. Gonínez-Fernández},
title = {Validation of a Na + - Ca ++ Regulation Model for High Variations of the Inner Cell Conditions},
journal ={Computer-Based Medical Systems, IEEE Symposium on},
volume = {0},
year = {2001},
isbn = {0-7695-1004-3},
pages = {0413},
doi = {http://doi.ieeecomputersociety.org/10.1109/CBMS.2001.941755},
publisher = {IEEE Computer Society},
address = {Los Alamitos, CA, USA},
}
 
 
RefWorks Procite/RefMan/Endnote
x 
 
TY - CONF
JO - Computer-Based Medical Systems, IEEE Symposium on
TI - Validation of a Na + - Ca ++ Regulation Model for High Variations of the Inner Cell Conditions
SN - 0-7695-1004-3
SP
EP
A1 - V. González-Vélez,
A1 - J. Aguilar-Pliego,
A1 - J.D. Morales-Guzmán,
A1 - J.R. Gonínez-Fernández,
PY - 2001
VL - 0
JA - Computer-Based Medical Systems, IEEE Symposium on
ER -
 
V. González-Vélez, UAM-Azapotzalco
J. Aguilar-Pliego, UAM-Azapotzalco
J.D. Morales-Guzmán, UAM-Azapotzalco
J.R. Gonínez-Fernández, UAM-Iztapalapa
Abstract: The Na+ - CA++ exchanger is a reversible regulation mechanism which can work for depleting or augmenting the internal Ca++ concentration, as long as there is enough quantity of free Na+. In previous papers we have showed some simulations of a Ca++ regulation simulator, including the Na+ - CA++ exchanger, which has demonstrated to be reliable for simulating the cell response to ionic and electric stimulus, providing the internal Ca++ concentration is in the physiologic range at the beginning of the simulation. In this paper, we pose several corrections to the original model and we also discuss the inclusion of additional kinetic and sensitivity parameters of the mechanisms in order to follow the biological role of the exchanging current.
Citation:
V. González-Vélez, J. Aguilar-Pliego, J.D. Morales-Guzmán, J.R. Gonínez-Fernández, "Validation of a Na + - Ca ++ Regulation Model for High Variations of the Inner Cell Conditions," cbms, pp.0413, 14th IEEE Symposium on Computer-Based Medical Systems (CMBS'01), 2001
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