Telemedicine involves the integration of information, telecommunications, human-machine and healthcare technologies. One of the aspects of telecardiology known as tele-electrocardiography deploys Electrocardiography machines to transmit Electrocardiograms (ECG) over networks. Tele-electrocardiography diagnosis and ECG interpretation is simple, reliable and cost-effective. As different parts of this tele-electrocardiography system work on different computing environments, software interoperability is a major issue. Software agent technology supports heterogeneous computing environment. As this technology reacts dynamically to adverse conditions, it is suitable for development of fault tolerant distributed systems. Additionally, agent technology represents the intentions, desires and resources of the participants - so it can be effectively used in on-line healthcare application. The features of software agent technology are potentially suitable for the development of interoperable telemedicine systems. This paper presents a software agent based interoperable scheme for tele-electrocardiography application.