2008 International Conference on BioMedical Engineering and Informatics
In Vivo Proton Magnetic Resonance Spectroscopic Study of the Healthy Chinese Adult Pons
May 27-May 30
ISBN: 978-0-7695-3118-2
Objective:??To detect the normal standard of metabolic ratios in the Pons of healthy adult Chinese subjects by using proton magnetic resonance spectroscopy (1HMRS). Materials and Methods:??Eighty healthy Chinese subjects were divided into four groups, containing of 20 subjects per decade, ranging 21 to 60 years. Spectra were obtained from at 1.5T MR scanner by using a PRESS sequence with Repetition Time (TR)/ Echo Time (TE) of 1500/144ms. Results:??The total mean ratios of N-acetylasparate/ creatine-phosphocreatine(NAA/Cr), NAA/Cr+ choline-containing compound(Cho) and Cho/Cr in subjects ranging from 21 to 60 years were 2.127?0.071, 0.811?0.059 and 1.814?0.094, respectively. The metabolic ratios in men were higher than in women. However, there was no significant difference with respect to age or gender. Conclusions: The ratios of NAA/Cr, NAA/Cr+Cho, Cho/Cr in the Pons did not correlate with age or gender of healthy subjects.
Index Terms:
Proton magnetic resonance spectroscopy, Pons, Metabolite
Citation:
J.T. Guan, X.H. Xu, Y.Q. Geng, X.J. Yu, R.H. Wu, "In Vivo Proton Magnetic Resonance Spectroscopic Study of the Healthy Chinese Adult Pons," bmei, vol. 2, pp.85-89, 2008 International Conference on BioMedical Engineering and Informatics, 2008