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2008 IEEE International Conference on Bioinformatics and Biomedicine
Functional Neighbors: Inferring Relationships between Non-Homologous Protein Families Using Family-Specific Packing Motifs
November 03-November 05
ISBN: 978-0-7695-3452-7
We describe a new approach for inferring the functional relationships between non-homologous protein families by looking at statistical enrichment of alternative function predictions in classification hierarchies such as Gene Ontology (GO) and Structural Classification of Proteins (SCOP).
Index Terms:
packing motifs, family-specific, structural motifs, protein function inference, protein function prediction, frequent subgraph mining, enrichment, functional neighbors, remote similarity, remote homology
Citation:
Deepak Bandyopadhyay, Jun (Luke) Huan, Jinze Liu, Jan Prins, Jack Snoeyink, Wei Wang, Alexander Tropsha, "Functional Neighbors: Inferring Relationships between Non-Homologous Protein Families Using Family-Specific Packing Motifs," bibm, pp.199-206, 2008 IEEE International Conference on Bioinformatics and Biomedicine, 2008
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