Technological advances in computers, diagnostic imaging, medical physics, biomedical engineering, and applied mathematics are the major driving forces in diagnosis and treatment.The term virtual reality (VR) refers to a human-computer interface that simulates a realistic environment while enabling user interaction.A virtual reality surgical simulator consists typically of five components, human body models (virtual patient), physical modeler, pathology modeler, virtual surgical instruments, and VR interface.Human body models are a critical component of a VR surgical simulator. These models encapsulate medical knowledge and provide means to predict, simulate, validate, and enhance the outcomes of diagnostic and surgical procedures.