Free flow of information is the feature that has made peer-to-peer information sharing applications popular. However, this very feature holds back the acceptance of these applications by the corporate and scientific communities. In these communities it is important to provide confidentiality and integrity of communication and to enforce access control to shared resources. We present a collection of security mechanisms that can be used to satisfy these security requirements. Our solutions are based on established and proven security techniques and we utilize existing technologies when possible. As a proof of concept, we have developed an information sharing system, called scishare, which integrates a number of these security mechanisms to provide a secure environment for information sharing. This system will allow a broader set of user communities to benefit from peer-to-peer information sharing.