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18th International Parallel and Distributed Processing Symposium (IPDPS'04) - Workshop 9
Constrained De Novo Peptide Identification via Multi-Objective Optimization
Santa Fe, New Mexico
April 26-April 30
ISBN: 0-7695-2132-0
J. M. Malard, Pacific Northwest National Laboratory
A. Heredia-Langner, Pacific Northwest National Laboratory
D. J. Baxter, Pacific Northwest National Laboratory
K. H. Jarman, Pacific Northwest National Laboratory
W. R. Cannon, Pacific Northwest National Laboratory
Automatic de novo peptide identification from collision-induced dissociation tandem mass spectrometry data is made difficult by large plateaus in the fitness landscapes of scoring functions and the fuzzy nature of the constraints that is due to noise in the data. Two different scoring functions are combined into a parallel multi-objective optimization framework.
Citation:
J. M. Malard, A. Heredia-Langner, D. J. Baxter, K. H. Jarman, W. R. Cannon, "Constrained De Novo Peptide Identification via Multi-Objective Optimization," ipdps, vol. 10, pp.191a, 18th International Parallel and Distributed Processing Symposium (IPDPS'04) - Workshop 9, 2004
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