Field-programmable analog arrays (FPAAs) provide a method for rapidly prototyping analog systems. Currently available commercial and academic FPAAs are typically based on operational ampli.ers (or other similar analog primitives) with only a few computational elements per chip. While their specific architectures vary, their small sizes and often restrictive interconnect designs leave current FPAAs limited in functionality, flexibility, and usefulness. In this paper, we explore the use of floating-gate devices as the core programmable element in a large-scale FPAA with applications in signal processing emphasized. An FPAA architecture is presented that offers increased functionality and flexibility in realizing analog signal processing systems, and experimental data from a testbed FPAA is shown. In addition, mainstream signal processing systems are discussed that can be effectively implemented on large-scale reconfigurable analog devices thereby realizing dramatic savings in power over traditional digital solutions and improved time-to-market over traditional analog designs.