In this paper, we describe a system called XomatiQ to address the problem of integration, querying and correlation of biological data. XomatiQ is an integral part of the genomics Research Network Architecture (gRNA). The gRNA provides the development environment in which new applications can be quickly written, and the deployment environment in which they can systematically avail of computing resources and integrate information from distributed biological data sources. Specifically, XomatiQ is build on top of the Data Hounds component. The Data Hounds transforms data from various sources to XML format and loads them into tuples of relational tables in a standard commercial DBMS. The XomatiQ provides capability for querying XML data using the underlying relational engine. XomatiQ has been fully implemented using Java.