It is a challenging task to provide Quality of Service (QoS) control for a shared high-speed downlink packet access (HSDPA) wireless channel. In this paper, we first propose a new dynamic resource control framework integrated with adaptive modulation and coding (AMC) and hybrid automatic repeat request (H-ARQ) to support class-based multimedia applications over HSDPA wireless channels. Then we present a new scheduling algorithm, Delay-sensitive Dynamic Fair Queueing (DSDFQ), to meet delay requirements of multimedia applications as well as maintain high network efficiency. The proposed approach can easily adapt to load fluctuations of different traffic classes and varying wireless channel conditions caused by user mobility, fading and shadowing. Performance evaluation shows the advantage of our proposed approach.