DDSTN03This paper explores how the Soft Information Systems and Technologies Methodology (SISTeM) and Actor Network Theory may be combined to address real world problematisations that lead to integrated human/machine interventions in the real world. An important component of this is the need for a modeling language for the multidimensional systemic representation of actor networks. The dimensions include human/machine activities, the information systems and technologies, clinical competencies, psychosocial relationships and power/politics. A scenario focusing on breast cancer treatment decision-making is used to illustrate the need for such a multidimensional modeling language and integrated interventions.