We propose a polynomial-time algorithm for optimal scalar quantizer design on discrete-alphabet sources. Special cases of the proposed approach yield optimal design algorithms for fixed-rate and entropy-constrained scalar quantizers, multi-resolution scalar quantizers, multiple description scalar quantizers, and Wyner-Ziv scalar quantizers. The algorithm guarantees globally optimal solutions for fixed-rate and entropy-constrained scalar quantizers and constrained optima for the other coding scenarios. We derive the algorithm by demonstrating the connection between scalar quantization, histogram segmentation, and the shortest path problem in a certain directed acyclic graph.