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2004 IEEE Computational Systems Bioinformatics Conference (CSB'04)
Bacillus Subtilis Protein Interaction Network Analysis
Stanford, California
August 16-August 19
ISBN: 0-7695-2194-0
Olusola C. Idowu, University of Newcastle upon Tyne
Steven J. Lynden, University of Newcastle upon Tyne
Malcolm P. Young, University of Newcastle upon Tyne
Peter Andras, University of Newcastle upon Tyne
Identifying functionally important proteins that are essential to the survival of a bacterial cell is of considerable interest in the development of new antimicrobial agents. Recent studies have shown that functionally important components in protein interaction networks may also be structurally important. We studied the protein interaction network of Bacillus subtilis to identify structurally essential proteins. Fifty-four percent of the structurally essential proteins identified by our methods were encoded by functionally essential genes.
Citation:
Olusola C. Idowu, Steven J. Lynden, Malcolm P. Young, Peter Andras, "Bacillus Subtilis Protein Interaction Network Analysis," csb, pp.623-625, 2004 IEEE Computational Systems Bioinformatics Conference (CSB'04), 2004
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