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Stacked Autoencoders for Unsupervised Feature Learning and Multiple Organ Detection in a Pilot Study Using 4D Patient Data
PrePrint
ISSN: 0162-8828
Hoo-Chang Shin, Institute of Cancer Rearch Royal Marsden NHS Foundation Trust, Sutton Sutton
Matthew R. Orton, Institute of Cancer Rearch Royal Marsden NHS Foundation Trust, Sutton Sutton
David J. Collins, Institute of Cancer Rearch Royal Marsden NHS Foundation Trust, Sutton Sutton
Simon J. Doran, Institute of Cancer Rearch Royal Marsden NHS Foundation Trust, Sutton Sutton
Martin O. Leach, Institute of Cancer Rearch Royal Marsden NHS Foundation Trust, Sutton Sutton
Medical image analysis remains a challenging application area for artificial intelligence. When applying machine learning, obtaining ground-truth labels for supervised learning is more difficult than in many more common applications of machine learning. This is especially so for datasets with abnormalities, as tissue types and the shapes of the organs in these datasets differ widely. However, organ detection in such an abnormal dataset may have many promising potential real world applications such as automatic diagnosis, automated radiotherapy planning, and medical image retrieval, where new multi-modal medical images provide more information about the imaged tissues for diagnosis. Here we test the application of deep learning methods to organ identification in magnetic resonance medical images, with visual and temporal hierarchical features learnt to categorise object classes from an unlabelled multi-modal DCE-MRI dataset, so that only a weakly supervised training is required for a classifier. A probabilistic patch-based method was employed for multiple organ detection, with the features learnt from the deep learning model. This shows the potential of the deep learning model for application to medical images, despite the difficulty of obtaining libraries of correctly labelled training datasets, and despite the intrinsic abnormalities present in patient datasets.
Index Terms:
Biomedical image processing,Computing Methodologies,Artificial Intelligence,Applications and Expert Knowledge-Intensive Systems,Computer vision,Machine learning,Learning,Edge and feature detection,Segmentation,Image Processing and Computer Vision,Pixel classification,Object recognition,Scene Analysis
Citation:
Hoo-Chang Shin, Matthew R. Orton, David J. Collins, Simon J. Doran, Martin O. Leach, "Stacked Autoencoders for Unsupervised Feature Learning and Multiple Organ Detection in a Pilot Study Using 4D Patient Data," IEEE Transactions on Pattern Analysis and Machine Intelligence, 31 Dec. 2012. IEEE computer Society Digital Library. IEEE Computer Society, <http://doi.ieeecomputersociety.org/10.1109/TPAMI.2012.277>
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