Issue No.07 - July (1972 vol.21)
R.S. Ledley , National Biomedical Research Foundation and the Department of Physiology and Biophysics, Georgetown University Medical School
Three methods approaching the analysis of cells are described, with applications. The methods presuppose that the picture of the cells has already been digitized and resides in the memory of a computer. The first method is an ad hoc approach in which intercommunicating programmable cursors are utilized for the detection of boundary and area features. The second method is concerned with an evaluation of the curvatures of boundary segments in relation to the overall shape of the boundary. The third method imbeds the picture in a non-Euclidean coordinate system, preserving as invariants salient features while negating the effect of nonsignificant distortions.
Cells, chromosomes, curvatures, cytology, languages, neurons, non-Euclidean, software, white blood cells.
R.S. Ledley, "Analysis of Cells", IEEE Transactions on Computers, vol.21, no. 7, pp. 740-753, July 1972, doi:10.1109/T-C.1972.223577