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Issue No.02 - March/April (2011 vol.8)
pp: 536-550
Michael D. Lieberman , University of Maryland, College Park
Sima Taheri , University of Maryland, College Park
Huimin Guo , University of Maryland, College Park
Fatemeh Mirrashed , University of Maryland, College Park
Inbal Yahav , University of Maryland, College Park
Aleks Aris , University of Maryland, College Park
Ben Shneiderman , University of Maryland, College Park
ABSTRACT
Though biomedical research often draws on knowledge from a wide variety of fields, few visualization methods for biomedical data incorporate meaningful cross-database exploration. A new approach is offered for visualizing and exploring a query-based subset of multiple heterogeneous biomedical databases. Databases are modeled as an entity-relation graph containing nodes (database records) and links (relationships between records). Users specify a keyword search string to retrieve an initial set of nodes, and then explore intra- and interdatabase links. Results are visualized with user-defined semantic substrates to take advantage of the rich set of attributes usually present in biomedical data. Comments from domain experts indicate that this visualization method is potentially advantageous for biomedical knowledge exploration.
INDEX TERMS
Data exploration and discovery, bioinformatics, information visualization.
CITATION
Michael D. Lieberman, Sima Taheri, Huimin Guo, Fatemeh Mirrashed, Inbal Yahav, Aleks Aris, Ben Shneiderman, "Visual Exploration across Biomedical Databases", IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol.8, no. 2, pp. 536-550, March/April 2011, doi:10.1109/TCBB.2010.1
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