This Article 
   
 Share 
   
 Bibliographic References 
   
 Add to: 
 
Digg
Furl
Spurl
Blink
Simpy
Google
Del.icio.us
Y!MyWeb
 
 Search 
   
Proceedings of the 1988 ACM/IEEE conference on Supercomputing vol. 2
Study of protein sequence comparison metrics on the Connection Machine CM-2
Orlando, FL, USA
November 14-November 18
ISBN: 0-8186-8923-4
Lander, Harvard Univ., Cambridge, MA, USA
Software tools have been developed to perform rapid large-scale protein sequence comparisons on databases of amino-acid sequences, using a data-parallel computer architecture. This software makes it possible to compare a protein against a database of several thousand proteins in the same time required by a conventional computer to do a single protein-protein comparison, thus enabling biologists to find relevant similarities much more quickly, and to evaluate many different comparison metrics in a reasonable period of time. This software was used to analyze the effectiveness of various scoring metrics in determining sequence similarity, and to generate statistical information about the behavior of these scoring systems under the variation of certain parameters.
Index Terms:
software tools, protein sequence comparison metrics, Connection Machine CM-2, databases, amino-acid sequences, data-parallel computer architecture, statistical information, scoring systems
Citation:
Lander, Mesirov, Taylor, "Study of protein sequence comparison metrics on the Connection Machine CM-2," sc, vol. 2, pp.2-12 vol.2, Proceedings of the 1988 ACM/IEEE conference on Supercomputing vol. 2, 1988
Usage of this product signifies your acceptance of the Terms of Use.