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2005 International Conference on MEMS,NANO and Smart Systems
Genetically Engineered Polypeptide for Differential Recognition of Platinum on Microfabricated Structures
Banff, Alberta, Canada
July 24-July 27
ISBN: 0-7695-2398-6
Mustafa Gungormus, Material Science and Engineering Department
Xiaorong Xiong, Department of Electrical Engineering
Candan Tamler, Material Science and Engineering Department
Babak A. Parviz, Department of Electrical Engineering,University of Washington, Seattle, WA 98195
Mehmet Sarikaya, Material Science and Engineering Department,University of Washington, Seattle, WA 98195

By evolution, nature has created an astonishing collection of micro and nano scale structures. In this paper, we discuss the development of a "molecular toolkit" which builds the basis for the biomimetic natural processes. As the first step, we have demonstrated the capability to identify polypeptides that specifically bind to an inorganic (platinum) and differentiate between this metal and other inorganic surfaces such as silicon dioxide and gold. We have achieved the integration of the polypeptides with a microfabricated heterogeneous substrate, by selectively immobilizing them on the specific inorganic materials. In the future, this "toolkit", integrating micro-, nano- and biotechnology, can be used for the development of new generation of biomimetic manufacturing process.

Citation:
Mustafa Gungormus, Xiaorong Xiong, Candan Tamler, Babak A. Parviz, Mehmet Sarikaya, "Genetically Engineered Polypeptide for Differential Recognition of Platinum on Microfabricated Structures," icmens, pp.167-171, 2005 International Conference on MEMS,NANO and Smart Systems, 2005
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