We formulate the problem of salient region detection in images as Markov random walks performed on images represented as graphs. While the global properties of the image are extracted from the random walk on a complete graph, the local properties are extracted from a k-regular graph. The most salient node is selected as the one which is globally most isolated but falls on a compact object. The equilibrium hitting times of the ergodic Markov chain holds the key for identifying the most salient node. The background nodes which are farthest from the most salient node are also identified based on the hitting times calculated from the random walk. Finally, a seeded salient region identification mechanism is developed to identify the salient parts of the image. The robustness of the proposed algorithm is objectively demonstrated with experiments carried out on a large image database annotated with ldquoground-truthrdquo salient regions.