Multi-tenancy technology is one of key competencies for network delivery services to achieve higher profit margin by leveraging the economic of scale. This paper explores the requirements and challenges of the native multi-tenancy pattern which have the potential of serving a large volume of clients simultaneously. We provide a framework with a set of multi-tenancy common services to help people design and implement a high quality native multi-tenant application more efficiently. Due to the essential requirement to guarantee service quality with high share efficiency, we present approaches and principles to support better isolations among tenants in many aspects such as security, performance, availability, administration etc. We have already achieved many hand on experiences by applying parts of the design and principles into a real multi-tenant application, and identified some future research points to better safeguard the quality of service for each tenant.