The Community for Technology Leaders
RSS Icon
Issue No.05 - Sept.-Oct. (2012 vol.27)
pp: 19-26
Qingfeng Chen , Guangxi University
Yi-Ping Phoebe Chen , La Trobe University
The inhibition of protein kinase activity can cause disease. The authors present a method for investigating inhibitive regulatory correlations between kinase isoforms and physical factors.
Itemsets, Proteins, Muscles, Artificial neural networks, Intelligent systems, data mining, protein kinase, activation, inhibition, pathway, negative-association rule
Qingfeng Chen, Yi-Ping Phoebe Chen, "Discovering Inhibition Pathways for Protein Kinases", IEEE Intelligent Systems, vol.27, no. 5, pp. 19-26, Sept.-Oct. 2012, doi:10.1109/MIS.2010.135
1. T. Carneiro et al., "Telomeres Avoid End Detection by Severing the Checkpoint Signal Transduction Pathway," Nature, vol. 467, no. 7312, 2010, pp. 228–232.
2. Q.F. Chen and Y.P.P. Chen, "Mining Frequent Patterns for AMP-Activated Protein Kinase Regulation on Skeletal Muscle," BMC Bioinformatics, vol. 7, no. 394, 2006;
3. R. Agrawal, T. Imielinski, and A. Swami, "Mining Association Rules Between Sets of Items in Large Databases," Proc. 1993 ACM SIGMOD Int'l Conf. Management of Data, ACM, 1993, pp. 207–216.
4. B. Bringmann et al., "Learning and Predicting the Evolution of Social Networks," IEEE Intelligent Systems, vol. 25, no. 4, 2010, pp. 26–35.
5. G. Gong et al., "Mining Top-K Covering Rule Groups for Gene Expression Data," Proc. 2005 ACM SIGMOD Int'l Conf. Management of Data, ACM, 2005, pp. 670–681.
6. X.D. Wu, C.Q. Zhang, and S.C. Zhang, "Efficient Mining of Both Positive and Negative-Association Rules," ACM Trans. Information Systems, vol. 22, no. 3, 2004, pp. 381–405.
7. Y.L. Cheung and A.W.C. Fu, "Mining Frequent Item Sets without Support Threshold: With and without Item Constraints," IEEE Trans. Knowledge and Data Engineering, vol. 16, no. 9, 2004, pp. 1052–1069.
8. V.A. Lira et al., "PGC-1alpha Regulation by Exercise Training and Its Influences on Muscle Function and Insulin Sensitivity," Am. J. Physiology—Endocrinology and Metabolism, vol. 299, no. 2, 2010, pp. 145–161.
9. N. Fujii et al., "Exercise Induces Isoform Specific Increase in 5′ AMP-Activated Protein Kinase Activity in Human Skeletal Muscle," Biochemical and Biophysical Research Communications, vol. 273, no. 3, 2000, pp. 1150–1155.
15 ms
(Ver 2.0)

Marketing Automation Platform Marketing Automation Tool