Issue No.06 - November/December (1999 vol.14)
This paper describes a methodology for building intelligent systems for mining biological sequences. The approach formalizes several key aspects of major bioinformatics systems that provide a functional annotation of newly sequenced genomes. The framework provides a high-level notation for specifying global genome structure, learning mechanisms for discovering genes, associating a function with hypothetical genes, and learning models for regulatory elements.
data mining, machine learning, computational genomics, bioinformatics
Simon Kasif, "Datascope: Mining Biological Sequences", IEEE Intelligent Systems, vol.14, no. 6, pp. 38-43, November/December 1999, doi:10.1109/MIS.1999.10031