Issue No.03 - May/June (1999 vol.1)
Over the past 10 to 15 years, numerous technical innovations have revolutionized molecular biology. These include the development of high-throughput DNA amplification techniques, improved DNA sequencing methods, more efficient procedures for determining protein structures, and new technologies for monitoring cellular processes at a global level. These breakthroughs have led to an explosion in the variety and quantity of data routinely generated in molecular biology research.
Jill P. Mesirov, "Guest Editors' Introduction: Computational Biology", Computing in Science & Engineering, vol.1, no. 3, pp. 16-17, May/June 1999, doi:10.1109/MCISE.1999.764211