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Exploring the Connectome: Petascale Volume Visualization of Microscopy Data Streams
July-Aug. 2013 (vol. 33 no. 4)
pp. 50-61
Johanna Beyer, King Abdullah University of Science and Technology
Markus Hadwiger, King Abdullah University of Science and Technology
Ali Al-Awami, King Abdullah University of Science and Technology
Won-Ki Jeong, Ulsan National Institute of Science and Technology
Narayanan Kasthuri, Harvard University
Jeff W. Lichtman, Harvard University
Hanspeter Pfister, Harvard University
Recent advances in high-resolution microscopy let neuroscientists acquire neural-tissue volume data of extremely large sizes. However, the tremendous resolution and the high complexity of neural structures present big challenges to storage, processing, and visualization at interactive rates. A proposed system provides interactive exploration of petascale (petavoxel) volumes resulting from high-throughput electron microscopy data streams. The system can concurrently handle multiple volumes and can support the simultaneous visualization of high-resolution voxel segmentation data. Its visualization-driven design restricts most computations to a small subset of the data. It employs a multiresolution virtual-memory architecture for better scalability than previous approaches and for handling incomplete data. Researchers have employed it for a 1-teravoxel mouse cortex volume, of which several hundred axons and dendrites as well as synapses have been segmented and labeled.
Index Terms:
Data visualization,Neuroscience,Image resolution,Rendering (computer graphics),Microscopy,Streaming media,Medical image processing,computer graphics,petascale-volume exploration,segmented volume data,high-resolution microscopy,high-throughput imaging,neuroscience
Johanna Beyer, Markus Hadwiger, Ali Al-Awami, Won-Ki Jeong, Narayanan Kasthuri, Jeff W. Lichtman, Hanspeter Pfister, "Exploring the Connectome: Petascale Volume Visualization of Microscopy Data Streams," IEEE Computer Graphics and Applications, vol. 33, no. 4, pp. 50-61, July-Aug. 2013, doi:10.1109/MCG.2013.55
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