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Visualizing Cells and Humans in 3D: Biomedical Image Analysis at Nanometer and Meter Scales
Sept.-Oct. 2012 (vol. 32 no. 5)
pp. 39-49
| ASCII Text | x | ||
| Terry S. Yoo, Donald Bliss, Bradley C. Lowekamp, David T. Chen, Gavin E. Murphy, Kedar Narayan, Lisa M. Hartnell, Thao Do, Sriram Subramaniam, "Visualizing Cells and Humans in 3D: Biomedical Image Analysis at Nanometer and Meter Scales," IEEE Computer Graphics and Applications, vol. 32, no. 5, pp. 39-49, Sept.-Oct., 2012. | |||
| BibTex | x | ||
| @article{ 10.1109/MCG.2012.68, author = {Terry S. Yoo and Donald Bliss and Bradley C. Lowekamp and David T. Chen and Gavin E. Murphy and Kedar Narayan and Lisa M. Hartnell and Thao Do and Sriram Subramaniam}, title = {Visualizing Cells and Humans in 3D: Biomedical Image Analysis at Nanometer and Meter Scales}, journal ={IEEE Computer Graphics and Applications}, volume = {32}, number = {5}, issn = {0272-1716}, year = {2012}, pages = {39-49}, doi = {http://doi.ieeecomputersociety.org/10.1109/MCG.2012.68}, publisher = {IEEE Computer Society}, address = {Los Alamitos, CA, USA}, } | |||
| RefWorks Procite/RefMan/Endnote | x | ||
| TY - MGZN JO - IEEE Computer Graphics and Applications TI - Visualizing Cells and Humans in 3D: Biomedical Image Analysis at Nanometer and Meter Scales IS - 5 SN - 0272-1716 SP39 EP49 EPD - 39-49 A1 - Terry S. Yoo, A1 - Donald Bliss, A1 - Bradley C. Lowekamp, A1 - David T. Chen, A1 - Gavin E. Murphy, A1 - Kedar Narayan, A1 - Lisa M. Hartnell, A1 - Thao Do, A1 - Sriram Subramaniam, PY - 2012 KW - Scanning electron microscopy KW - Nanobioscience KW - Image resolution KW - Biomedical image processing KW - Human factors KW - Science - general KW - Pattern recognition KW - Visualization KW - Computational modeling KW - pattern recognition KW - Scanning electron microscopy KW - Nanobioscience KW - Image resolution KW - Biomedical image processing KW - Human factors KW - Science - general KW - Pattern recognition KW - Visualization KW - Computational modeling KW - computer graphics KW - life and medical sciences KW - computer applications KW - visualization techniques and methodologies KW - simulation KW - modeling KW - visualization KW - segmentation KW - image processing KW - computer vision computing methodologies KW - volume visualization VL - 32 JA - IEEE Computer Graphics and Applications ER - | |||
DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/MCG.2012.68
Researchers analyzed and presented volume data from the Visible Human Project (VHP) and data from high-resolution 3D ion-abrasion scanning electron microscopy (IA-SEM). They acquired the VHP data using cryosectioning, a destructive approach to 3D human anatomical imaging resulting in whole-body images with a field of view approaching 2 meters and a minimum resolvable feature size of 300 microns. IA-SEM is a type of block-face imaging microscopy, a destructive approach to microscopic 3D imaging of cells. The field of view of IA-SEM data is on the order of 10 microns (whole cell) with a minimum resolvable feature size of 15 nanometers (single-slice thickness). Despite the difference in subject and scale, the analysis and modeling methods were remarkably similar. They are derived from image processing, computer vision, and computer graphics techniques. Moreover, together we are employing medical illustration, visualization, and rapid prototyping to inform and inspire biomedical science. By combining graphics and biology, we are imaging across nine orders of magnitude of space to better promote public health through research.
Index Terms:
Scanning electron microscopy,Nanobioscience,Image resolution,Biomedical image processing,Human factors,Science - general,Pattern recognition,Visualization,Computational modeling,pattern recognition,Scanning electron microscopy,Nanobioscience,Image resolution,Biomedical image processing,Human factors,Science - general,Pattern recognition,Visualization,Computational modeling,computer graphics,life and medical sciences,computer applications,visualization techniques and methodologies,simulation,modeling,visualization,segmentation,image processing,computer vision computing methodologies,volume visualization
Citation:
Terry S. Yoo, Donald Bliss, Bradley C. Lowekamp, David T. Chen, Gavin E. Murphy, Kedar Narayan, Lisa M. Hartnell, Thao Do, Sriram Subramaniam, "Visualizing Cells and Humans in 3D: Biomedical Image Analysis at Nanometer and Meter Scales," IEEE Computer Graphics and Applications, vol. 32, no. 5, pp. 39-49, Sept.-Oct. 2012, doi:10.1109/MCG.2012.68
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